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A minority of carcinoma cells producing acidic fibroblast growth factor induces a community effect for tumor progression.

It is generally accepted that primary tumors become heterogeneous as a consequence of tumor-cell genetic instability. Clonal dominance has been shown to occur in some experimental models allowing a subpopulation of cells to overgrow the primary heterogeneous tumor and to metastasize. Alternatively,...

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Bibliographic Details
Main Authors: Jouanneau, J, Moens, G, Bourgeois, Y, Poupon, M F, Thiery, J P
Format: Artigo
Language:Inglês
Published: 1994
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC42932/
https://ncbi.nlm.nih.gov/pubmed/7506417
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