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N-acetylcysteine inhibits the upregulation of mitochondrial biogenesis genes in livers from rats fed ethanol chronically

BACKGROUND: Chronic ethanol administration to experimental animals induces hepatic oxidative stress and upregulates mitochondrial biogenesis. The mechanisms by which chronic ethanol upregulates mitochondrial biogenesis have not been fully explored. In this work, we hypothesized that oxidative stress...

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Detalhes bibliográficos
Publicado no:Alcohol Clin Exp Res
Main Authors: Caro, Andres A., Bell, Matthew, Ejiofor, Shannon, Zurcher, Grant, Petersen, Dennis R., Ronis, Martin J. J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293075/
https://ncbi.nlm.nih.gov/pubmed/25581647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12576
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