Synergistic Effect of β-Amyloid and Neurodegeneration on Cognitive Decline in Clinically Normal Individuals

IMPORTANCE: Assessing the ability of Alzheimer disease neuroimaging markers to predict short-term cognitive decline among clinically normal (CN) individuals is critical for upcoming secondary prevention trials using cognitive outcomes. OBJECTIVE: To determine whether neuroimaging markers of β-amyloi...

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Pubblicato in:JAMA Neurol
Autori principali: Mormino, Elizabeth C., Betensky, Rebecca A., Hedden, Trey, Schultz, Aaron P., Amariglio, Rebecca E., Rentz, Dorene M., Johnson, Keith A., Sperling, Reisa A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4293023/
https://ncbi.nlm.nih.gov/pubmed/25222039
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2014.2031
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