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Morphine-induced internalization of the L83I mutant of the rat μ-opioid receptor
BACKGROUND AND PURPOSE: Naturally occurring single-nucleotide polymorphisms (SNPs) within GPCRs can result in alterations in various pharmacological parameters. Understanding the regulation and function of endocytic trafficking of the μ-opioid receptor (MOP receptor) is of great importance given its...
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Publicado en: | Br J Pharmacol |
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Autores principales: | , , , , , |
Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Blackwell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292971/ https://ncbi.nlm.nih.gov/pubmed/24697554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12709 |
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