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Treatment of Influenza Infection of Mice by Using Rimantadine Hydrochlorides by the Aerosol and Intraperitoneal Routes

Rimantadine hydrochloride was administered for 4 days in a small-particle (95% < 6.5 μm) aerosol (8.8 mg/kg per day) or intraperitoneally (40 mg/kg per day) to mice previously infected with influenza A/Aichi/2/68 (H(3)N(2)), mouse adapted. Mean time to death and incidence of survival were signifi...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Stephen, Edward L., Dominik, Joseph W., Moe, James B., Spertzel, Richard O., Walker, Jerry S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1975
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429282/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1180541/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.2.154
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