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Treatment of Influenza Infection of Mice by Using Rimantadine Hydrochlorides by the Aerosol and Intraperitoneal Routes

Rimantadine hydrochloride was administered for 4 days in a small-particle (95% < 6.5 μm) aerosol (8.8 mg/kg per day) or intraperitoneally (40 mg/kg per day) to mice previously infected with influenza A/Aichi/2/68 (H(3)N(2)), mouse adapted. Mean time to death and incidence of survival were signifi...

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Autors principals: Stephen, Edward L., Dominik, Joseph W., Moe, James B., Spertzel, Richard O., Walker, Jerry S.
Format: Artigo
Idioma:Inglês
Publicat: 1975
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC429282/
https://ncbi.nlm.nih.gov/pubmed/1180541
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