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Action of Polymyxin B on Bacterial Membranes: Morphological Changes in the Cytoplasm and in the Outer Membrane of Salmonella typhimurium and Escherichia coli B

Though the primary action of the cationic antibiotic polymyxin B is against the membrane of susceptible bacteria, severe morphological changes are detected in the cytoplasm. Using fluorescence microscopy and a mono-N-dansyl-polymyxin B derivative, we could demonstrate aggregations of the antibiotic...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Schindler, Peter R. G., Teuber, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1975
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429267/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/169730/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.8.1.95
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