Saturation mutagenesis of a polyadenylation signal reveals a hexanucleotide element essential for mRNA 3' end formation in Saccharomyces cerevisiae.

The cis-acting signal sequences required for mRNA 3' end formation are highly conserved and well characterized in higher eukaryotes. However, the situation in the yeast Saccharomyces cerevisiae is still unclear. Several sequences have been proposed which share only limited similarities. One difficul...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Irniger, S, Braus, G H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1994
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42926/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278376/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.257
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