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Limitations of bystander killing in Th1/M1 immune responses against a secreted tumor antigen
T-cell recognition of tumor antigens presented on tumor-infiltrating macrophages (TAMs) induces a tumoricidal M1-like phenotype. Resultant indirect immune responses could eliminate not only antigen secreting (Ag(POS)), but also antigen negative (Ag(NEG)) tumor cells via bystander killing. Such broad...
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| Pubblicato in: | Oncoimmunology |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4292458/ https://ncbi.nlm.nih.gov/pubmed/25941607 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.954953 |
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