The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.

Water balance in the lung is controlled via active Na+ and Cl- transport. Electrophysiological measurements on lung epithelial cells demonstrated the presence of a Na+ channel that is inhibited by amiloride (K0.5 = 90 nM) and some of its derivatives such as phenamil (K0.5 = 19 nM) and benzamil (K0.5...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Voilley, N, Lingueglia, E, Champigny, G, Mattéi, M G, Waldmann, R, Lazdunski, M, Barbry, P
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42924/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278374/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.247
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