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The lung amiloride-sensitive Na+ channel: biophysical properties, pharmacology, ontogenesis, and molecular cloning.

Water balance in the lung is controlled via active Na+ and Cl- transport. Electrophysiological measurements on lung epithelial cells demonstrated the presence of a Na+ channel that is inhibited by amiloride (K0.5 = 90 nM) and some of its derivatives such as phenamil (K0.5 = 19 nM) and benzamil (K0.5...

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Detalhes bibliográficos
Main Authors: Voilley, N, Lingueglia, E, Champigny, G, Mattéi, M G, Waldmann, R, Lazdunski, M, Barbry, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42924/
https://ncbi.nlm.nih.gov/pubmed/8278374
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