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Leber Congenital Amaurosis Caused by Mutations in GUCY2D

Leber congenital amaurosis (LCA) is a clinically and genetically heterogeneous group of diseases that account for the most severe form of early-onset retinal dystrophy. Mutations in retinal guanylate cyclase-1 (GUCY2D) are associated with LCA1, a prevalent form. GUCY2D encodes guanylate cyclase-1 (G...

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Pubblicato in:Cold Spring Harb Perspect Med
Autore principale: Boye, Shannon E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292079/
https://ncbi.nlm.nih.gov/pubmed/25256176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a017350
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