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Synthetic Chemically Modified mRNA (modRNA): Toward a New Technology Platform for Cardiovascular Biology and Medicine

Over the past two decades, a host of new molecular pathways have been uncovered that guide mammalian heart development and disease. The ability to genetically manipulate these pathways in vivo have largely been dependent on the generation of genetically engineered mouse model systems or the transfer...

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Publicado en:Cold Spring Harb Perspect Med
Autores principales: Chien, Kenneth R., Zangi, Lior, Lui, Kathy O.
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292072/
https://ncbi.nlm.nih.gov/pubmed/25301935
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a014035
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