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The phosphoinositide-binding protein TRAF4 modulates tight junction stability and migration of cancer cells

Tumor necrosis factor (TNF) receptor-associated factor 4 (TRAF4), a protein localized in TJs in normal epithelial cells, is frequently overexpressed in carcinomas. We recently found that TRAF4 impedes TJ formation/stability and favors cell migration, 2 hallmarks of cancer progression. In addition TR...

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Bibliografiska uppgifter
I publikationen:Tissue Barriers
Huvudupphovsmän: Rousseau, Adrien, Wilhelm, Léa P, Tomasetto, Catherine, Alpy, Fabien
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4292048/
https://ncbi.nlm.nih.gov/pubmed/25610759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21688370.2014.975597
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