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Glutamate Dehydrogenase Specific Activity and Cephalosporin C Synthesis in the M8650 Series of Cephalosporium acremonium Mutants

Conditions for the accurate measure of glutamic dehydrogenase (GDH) from Cephalosporium acremonium were determined. K(m) values for α-ketoglutarate and ammonium ion were 7 and 15 mM, respectively. The half-saturation for reduced nicotinamide adenine dinucleotide phosphate was 5 μM. Reduced nicotinam...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Queener, S. W., McDermott, J., Radue, A. B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1975
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC429196/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1170808/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.7.5.646
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