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Mining Soil Metagenomes to Better Understand the Evolution of Natural Product Structural Diversity: Pentangular Polyphenols as a Case Study

[Image: see text] Sequence-guided mining of metagenomic libraries provides a means of recovering specific natural product gene clusters of interest from the environment. In this study, we use ketosynthase gene (KS) PCR amplicon sequences (sequence tags) to explore the structural and biosynthetic div...

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Publicat a:J Am Chem Soc
Autors principals: Kang, Hahk-Soo, Brady, Sean F.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2014
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291760/
https://ncbi.nlm.nih.gov/pubmed/25521786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja510606j
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