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Mining Soil Metagenomes to Better Understand the Evolution of Natural Product Structural Diversity: Pentangular Polyphenols as a Case Study

[Image: see text] Sequence-guided mining of metagenomic libraries provides a means of recovering specific natural product gene clusters of interest from the environment. In this study, we use ketosynthase gene (KS) PCR amplicon sequences (sequence tags) to explore the structural and biosynthetic div...

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Detalhes bibliográficos
Publicado no:J Am Chem Soc
Main Authors: Kang, Hahk-Soo, Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291760/
https://ncbi.nlm.nih.gov/pubmed/25521786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja510606j
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