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Mining Soil Metagenomes to Better Understand the Evolution of Natural Product Structural Diversity: Pentangular Polyphenols as a Case Study

[Image: see text] Sequence-guided mining of metagenomic libraries provides a means of recovering specific natural product gene clusters of interest from the environment. In this study, we use ketosynthase gene (KS) PCR amplicon sequences (sequence tags) to explore the structural and biosynthetic div...

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Detalles Bibliográficos
Publicado en:J Am Chem Soc
Main Authors: Kang, Hahk-Soo, Brady, Sean F.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2014
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291760/
https://ncbi.nlm.nih.gov/pubmed/25521786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja510606j
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