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Mining Soil Metagenomes to Better Understand the Evolution of Natural Product Structural Diversity: Pentangular Polyphenols as a Case Study

[Image: see text] Sequence-guided mining of metagenomic libraries provides a means of recovering specific natural product gene clusters of interest from the environment. In this study, we use ketosynthase gene (KS) PCR amplicon sequences (sequence tags) to explore the structural and biosynthetic div...

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Vydáno v:J Am Chem Soc
Hlavní autoři: Kang, Hahk-Soo, Brady, Sean F.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291760/
https://ncbi.nlm.nih.gov/pubmed/25521786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja510606j
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