Chemically Synthesized Molecules with the Targeting and Effector Functions of Antibodies

[Image: see text] This article reports the design, synthesis, and evaluation of a novel class of molecules of intermediate size (approximately 7000 Da), which possess both the targeting and effector functions of antibodies. These compounds—called synthetic antibody mimics targeting prostate cancer (...

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Vydáno v:J Am Chem Soc
Hlavní autoři: McEnaney, Patrick J., Fitzgerald, Kelly J., Zhang, Andrew X., Douglass, Eugene F., Shan, Weifang, Balog, Aaron, Kolesnikova, Mariya D., Spiegel, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2014
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291750/
https://ncbi.nlm.nih.gov/pubmed/25514603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja509513c
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