Overproduction of the MtrCDE Efflux Pump in Neisseria gonorrhoeae Produces Unexpected Changes in Cellular Transcription Patterns

The global consequence of drug efflux gene overexpression in bacteria has not been specifically analyzed because strains showing high-level expression typically have mutations in genes encoding regulatory proteins that control other genes. Results from a transcriptional profiling study performed wit...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Ohneck, Elizabeth A., Goytia, Maira, Rouquette-Loughlin, Corinne E., Joseph, Sandeep J., Read, Timothy D., Jerse, Ann E., Shafer, William M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Mechanisms of Resistance
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291417/
https://ncbi.nlm.nih.gov/pubmed/25367915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04148-14
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