Effect of Rifampin and Rifabutin on Serum Itraconazole Levels in Patients with Chronic Pulmonary Aspergillosis and Coexisting Nontuberculous Mycobacterial Infection

We investigated the effects of rifampin and rifabutin on serum itraconazole levels in patients with chronic pulmonary aspergillosis. Serum itraconazole concentrations were significantly lower in patients who received itraconazole with rifampin (median, 0.1 μg/ml; P < 0.001) or rifabutin (median,...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Moon, Seong Mi, Park, Hye Yun, Jeong, Byeong-Ho, Jeon, Kyeongman, Lee, Soo-Youn, Koh, Won-Jung
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Clinical Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291413/
https://ncbi.nlm.nih.gov/pubmed/25313207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04075-14
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