Prenatal immune challenge in rats: Effects of polyinosinic-polycytidylic acid on spatial learning, prepulse inhibition, conditioned fear, and responses to MK-801 and amphetamine

Prenatal maternal immune activation increases risk for schizophrenia and/or autism. Previous data suggest that maternal weight change in response to the immune activator polyinosinic-polycytidylic (Poly IC) in rats influences the severity of effect in the offspring as does the exposure period. We tr...

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Detalhes bibliográficos
Publicado no:Neurotoxicol Teratol
Main Authors: Vorhees, Charles V., Graham, Devon L., Braun, Amanda A., Schaefer, Tori L., Skelton, Matthew R., Richtand, Neil M., Williams, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291316/
https://ncbi.nlm.nih.gov/pubmed/25450663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ntt.2014.10.007
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