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Mutant prevention concentration of tigecycline for clinical isolates of Streptococcus pneumoniae and Staphylococcus aureus

BACKGROUND: The mutant prevention concentration (MPC) reflects the antimicrobial susceptibility of the resistant mutant subpopulations present in large bacterial populations. In principle, combining the MPC with pharmacokinetic measurements can guide treatment to restrict the enrichment of resistant...

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Détails bibliographiques
Publié dans:J Antimicrob Chemother
Auteurs principaux: Hesje, C. K., Drlica, K., Blondeau, J. M.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291236/
https://ncbi.nlm.nih.gov/pubmed/25324419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dku389
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