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The Crystal Structure of GCAP3 Suggests Molecular Mechanism of GCAP–linked Cone Dystrophies

Absorption of light by visual pigments initiates the phototransduction pathway that results in degradation of the intracellular pool of cyclic–GMP (cGMP). This hydrolysis promotes the closing of cGMP–gated cation channels and consequent hyperpolarization of rod and cone photoreceptor cell membranes....

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Stephen, Ricardo, Palczewski, Krzysztof, Sousa, Marcelo C.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291230/
https://ncbi.nlm.nih.gov/pubmed/16626734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2006.03.042
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