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Optical Clearing in Dense Connective Tissues to Visualize Cellular Connectivity In Situ

Visualizing the three-dimensional morphology and spatial patterning of cells embedded deep within dense connective tissues of the musculoskeletal system has been possible only by utilizing destructive techniques. Here we utilize fructose-based clearing solutions to image cell connectivity and deep t...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Calve, Sarah, Ready, Andrew, Huppenbauer, Christopher, Main, Russell, Neu, Corey P.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291226/
https://ncbi.nlm.nih.gov/pubmed/25581165
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0116662
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