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A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

Activation of transcription by the promoter-specific factor Sp1 requires coactivators that are tightly associated with the TATA-box-binding protein (TBP) in the TFIID complex. Recent work has shown that the two glutamine-rich activation domains of Sp1, A and B, can interact with at least one compone...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Gill, G, Pascal, E, Tseng, Z H, Tjian, R
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42912/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278363/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.192
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