Stroma-Derived Interleukin-34 Controls the Development and Maintenance of Langerhans Cells and the Maintenance of Microglia

Colony stimulating factor-1 (Csf-1) receptor and its ligand Csf-1 control macrophage development, maintenance, and function. The development of both Langerhans cells (LCs) and microglia is highly dependent on Csf-1 receptor signaling but independent of Csf-1. Here we show that in both mice and human...

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Vydáno v:Immunity
Hlavní autoři: Greter, Melanie, Lelios, Iva, Pelczar, Pawel, Hoeffel, Guillaume, Price, Jeremy, Leboeuf, Marylene, Kündig, Thomas M., Frei, Karl, Ginhoux, Florent, Merad, Miriam, Becher, Burkhard
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4291117/
https://ncbi.nlm.nih.gov/pubmed/23177320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.11.001
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