Effects of caffeine on circadian phase, amplitude and period evaluated in cells in vitro and peripheral organs in vivo in PER2::LUCIFERASE mice

BACKGROUND AND PURPOSE: Caffeine is one of the most commonly used psychoactive substances. Circadian rhythms consist of the main suprachiasmatic nucleus (SCN) clocks and peripheral clocks. Although caffeine lengthens circadian rhythms and modifies phase changes in SCN-operated rhythms, the effects o...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Narishige, Seira, Kuwahara, Mari, Shinozaki, Ayako, Okada, Satoshi, Ikeda, Yuko, Kamagata, Mayo, Tahara, Yu, Shibata, Shigenobu
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290722/
https://ncbi.nlm.nih.gov/pubmed/25160990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12890
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