Network-based biomarkers enhance classical approaches to prognostic gene expression signatures

BACKGROUND: Classical approaches to predicting patient clinical outcome via gene expression information are primarily based on differential expression of unrelated genes (single-gene approaches) or genes related by, for example, biologic pathway or function (gene-sets). Recently, network-based appro...

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Udgivet i:BMC Syst Biol
Main Authors: Barter, Rebecca L, Schramm, Sarah-Jane, Mann, Graham J, Yang, Yee Hwa
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290694/
https://ncbi.nlm.nih.gov/pubmed/25521200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-8-S4-S5
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