Functional Aspects of the Solution Structure and Dynamics of PAF, a Highly Stable Antifungal Protein from Penicillium chrysogenum

PAF is a promising antimycotic without toxic effects on mammalian cells and therefore may be a drug candidate against the often lethal Aspergillus infections in human. The pathogenesis of PAF on sensitive fungi involves G-protein coupled signaling followed by apoptosis. Here, the solution structure...

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Udgivet i:FEBS J
Main Authors: Batta, Gyula, Barna, Teréz, Gáspári, Zoltán, Sándor, Szabolcs, Kövér, Katalin E., Binder, Ulrike, Sarg, Bettina, Kaiserer, Lydia, Chhillar, Anil Kumar, Eigentler, Andrea, Leiter, Éva, Hegedüs, Nikoletta, Pócsi, István, Lindner, Herbert, Marx, Florentine
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4290664/
https://ncbi.nlm.nih.gov/pubmed/19459942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2009.07011.x
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