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Supervised prediction of drug-induced nephrotoxicity based on interleukin-6 and -8 expression levels
BACKGROUND: Drug-induced nephrotoxicity causes acute kidney injury and chronic kidney diseases, and is a major reason for late-stage failures in the clinical trials of new drugs. Therefore, early, pre-clinical prediction of nephrotoxicity could help to prioritize drug candidates for further evaluati...
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| Wydane w: | BMC Bioinformatics |
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| Główni autorzy: | , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2014
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4290648/ https://ncbi.nlm.nih.gov/pubmed/25521947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-15-S16-S16 |
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