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Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
BACKGROUND: Cancers arise from multiple acquired mutations, which presumably occur over many years. Early stages in cancer development might be present years before cancers become clinically apparent. METHODS: We analyzed data from whole-exome sequencing of DNA in peripheral-blood cells from 12,380...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | N Engl J Med |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
2014
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4290021/ https://ncbi.nlm.nih.gov/pubmed/25426838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1056/NEJMoa1409405 |
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