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Mutations in Escherichia coli K-12 Decreasing the Rate of Streptomycin Uptake: Synergism with R-Factor-Mediated Capacity to Inactivate Streptomycin

Escherichia coli K-12 carrying the R-factor R1 or R6K is resistant to streptomycin. The resistance is due to R-factor-coded enzymes that metabolize the drug. Streptomycin can be inactivated in two ways, either by adenylylation or by phosphorylation; both reactions require adenosine 5′-triphosphate....

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Detalhes bibliográficos
Main Authors: Lundbäck, Annika K., Nordström, Kurt
Formato: Artigo
Idioma:Inglês
Publicado em: 1974
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC429002/
https://ncbi.nlm.nih.gov/pubmed/4618460
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