Recombination is a key driver of genomic and phenotypic diversity in a Pseudomonas aeruginosa population during cystic fibrosis infection

The Cystic Fibrosis (CF) lung harbors a complex, polymicrobial ecosystem, in which Pseudomonas aeruginosa is capable of sustaining chronic infections, which are highly resistant to multiple antibiotics. Here, we investigate the phenotypic and genotypic diversity of 44 morphologically identical P. ae...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Darch, Sophie E., McNally, Alan, Harrison, Freya, Corander, Jukka, Barr, Helen L., Paszkiewicz, Konrad, Holden, Stephen, Fogarty, Andrew, Crusz, Shanika A., Diggle, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289893/
https://ncbi.nlm.nih.gov/pubmed/25578031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07649
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