Heterogeneous sensitivity of human Acute Myeloid Leukemia to ß-catenin down-modulation

Dysregulation of the Wnt/ß-catenin pathway has been observed in various malignancies, including acute myeloid leukemia (AML), where the over-expression of ß-catenin is an independent adverse prognostic factor. ß-catenin was found up-regulated in the vast majority of AML samples and more frequently l...

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Gepubliceerd in:Leukemia
Hoofdauteurs: Gandillet, Arnaud, Park, Sophie, Lassailly, François, Griessinger, Emmanuel, Vargaftig, Jacques, Filby, Andrew, Lister, T. Andrew, Bonnet, Dominique
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289854/
https://ncbi.nlm.nih.gov/pubmed/21339756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2011.17
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