Anti-CD3 antibody induces long-term remission of overt autoimmunity in nonobese diabetic mice.

Anti-CD3 monoclonal antibodies suppress immune responses by transient T-cell depletion and antigenic modulation of the CD3/T-cell receptor complex. Anti-CD3 treatment of adult nonobese diabetic (NOD) mice, a spontaneous model of T-cell-mediated autoimmune insulin-dependent diabetes mellitus, signifi...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Chatenoud, L, Thervet, E, Primo, J, Bach, J F
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42898/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8278351/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.1.123
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