HLA-DPB1 and HLA Class I Confer Risk of and Protection from Narcolepsy

Type 1 narcolepsy, a disorder caused by a lack of hypocretin (orexin), is so strongly associated with human leukocyte antigen (HLA) class II HLA-DQA1(∗)01:02-DQB1(∗)06:02 (DQ0602) that very few non-DQ0602 cases have been reported. A known triggering factor for narcolepsy is pandemic 2009 influenza H...

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Publicat a:Am J Hum Genet
Autors principals: Ollila, Hanna M., Ravel, Jean-Marie, Han, Fang, Faraco, Juliette, Lin, Ling, Zheng, Xiuwen, Plazzi, Giuseppe, Dauvilliers, Yves, Pizza, Fabio, Hong, Seung-Chul, Jennum, Poul, Knudsen, Stine, Kornum, Birgitte R., Dong, Xiao Song, Yan, Han, Hong, Heeseung, Coquillard, Cristin, Mahlios, Joshua, Jolanki, Otto, Einen, Mali, Lavault, Sophie, Högl, Birgit, Frauscher, Birgit, Crowe, Catherine, Partinen, Markku, Huang, Yu Shu, Bourgin, Patrice, Vaarala, Outi, Désautels, Alex, Montplaisir, Jacques, Mack, Steven J., Mindrinos, Michael, Fernandez-Vina, Marcelo, Mignot, Emmanuel
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289679/
https://ncbi.nlm.nih.gov/pubmed/25574827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2014.12.010
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