The long and short of it: the influence of N-carboxyethyl versus N-carboxymethyl pendant arms on in vitro and in vivo behavior of copper complexes of cross-bridged tetraamine macrocycles

A cross-bridged cyclam ligand bearing two N-carboxymethyl pendant arms (1) has been found to form a copper(II) complex that exhibits significantly improved biological behavior in recent research towards (64)Cu-based radiopharmaceuticals. Both the kinetic inertness and resistance to reduction of Cu–1...

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Publicado en:Dalton Trans
Main Authors: Heroux, Katie J., Woodin, Katrina S., Tranchemontagne, David J., Widger, Peter C. B., Southwick, Evan, Wong, Edward H., Weisman, Gary R., Tomellini, Sterling A., Wadas, Thaddeus J., Anderson, Carolyn J., Kassel, Scott, Golen, James A., Rheingold, Arnold L.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289607/
https://ncbi.nlm.nih.gov/pubmed/17514336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/b702938a
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