Simultaneous silencing of VEGF and KSP by siRNA cocktail inhibits proliferation and induces apoptosis of hepatocellular carcinoma Hep3B cells

BACKGROUND: Vascular endothelial growth factor (VEGF) is involved in the growth of new blood vessels that feed tumors and kinesin spindle protein (KSP) plays a critical role in mitosis involving in cell proliferation. Simultaneous silencing of VEGF and KSP, an attractive and viable approach in cance...

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Bibliographic Details
Published in:Biol Res
Main Authors: Doan, Chung Chinh, Le, Long Thanh, Hoang, Son Nghia, Do, Si Minh, Le, Dong Van
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4289546/
https://ncbi.nlm.nih.gov/pubmed/25723613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/0717-6287-47-70
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