Chemical Characterization of Ethambutol Binding to Mycobacterium smegmatis

Recent studies showed that critical binding of ethambutol to Mycobacterium smegmatis was both inhibited and reversed by ions. This apparent ion-susceptible characteristic suggested that ethambutol is held at critical sites by electrostatic bonds. Dissociation constant, pH, and ionic strength studies...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Beggs, William H., Andrews, Fred A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1974
Assuntos:	Articles
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC428954/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4840434/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.5.3.234
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