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Sulfhydryl Reactivity: Mechanism of Action of Several Antiviral Compounds—Selenocystine, 4-(2-Propinyloxy)-β-Nitrostyrene, and Acetylaranotin

The addition of 5 mM dithiothreitol to a cell-free assay system for influenza ribonucleic acid (RNA) polymerase activity reverses the inhibitory activity otherwise possessed by three established antiviral compounds: selenocystine, 4-(2-propinyloxy)-β-nitrostyrene, and acetylaranotin. Although 50% or...

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Dettagli Bibliografici
Autori principali: Billard, William, Peets, Edwin
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1974
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC428913/
https://ncbi.nlm.nih.gov/pubmed/4840446
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