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Construction of libraries enriched for sequence repeats and jumping clones, and hybridization selection for region-specific markers.

We describe a simple and rapid method for constructing small-insert genomic libraries highly enriched for dimeric, trimeric, and tetrameric nucleotide repeat motifs. The approach involves use of DNA inserts recovered by PCR amplification of a small-insert sonicated genomic phage library or by a sing...

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Bibliografske podrobnosti
Main Authors: Kandpal, R P, Kandpal, G, Weissman, S M
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC42891/
https://ncbi.nlm.nih.gov/pubmed/8278412
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