Accumulation-Associated Protein Enhances Staphylococcus epidermidis Biofilm Formation under Dynamic Conditions and Is Required for Infection in a Rat Catheter Model

Biofilm formation is the primary virulence factor of Staphylococcus epidermidis. S. epidermidis biofilms preferentially form on abiotic surfaces and may contain multiple matrix components, including proteins such as accumulation-associated protein (Aap). Following proteolytic cleavage of the A domai...

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Détails bibliographiques
Publié dans:Infect Immun
Auteurs principaux: Schaeffer, Carolyn R., Woods, Keith M., Longo, G. Matt, Kiedrowski, Megan R., Paharik, Alexandra E., Büttner, Henning, Christner, Martin, Boissy, Robert J., Horswill, Alexander R., Rohde, Holger, Fey, Paul D.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Molecular Pathogenesis
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288872/
https://ncbi.nlm.nih.gov/pubmed/25332125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02177-14
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