Combination immunotherapy with anti-CTLA-4 and interleukin-2 redirects regulatory T cells into tumor-draining lymph nodes and expands anti-tumor CD8+ T cells in the tumor microenvironment

Samankaltaisia teoksia

• Combination immunotherapy with Interleukin-2 and CTLA-4 blockade decreases tumor growth and improves overall survival
  Tekijä: Broucek, Joseph R, et al.
  Julkaistu: (2013)
• Acute viral infection results in a PD-1-dependent loss of anti-tumor CD8+ T cell responses: implications for tumor immunotherapy
  Tekijä: Kohlhapp, Frederick, et al.
  Julkaistu: (2015)
• PD-1 blockade reverses viral infection-induced loss of anti-tumor CD8+ T cell responses
  Tekijä: Huelsmann, Erica, et al.
  Julkaistu: (2013)
• NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade
  Tekijä: Kohlhapp, Frederick J, et al.
  Julkaistu: (2015)
• Role of dose selection in successful interleukin-2 immunotherapy: solving the Goldilock’s Complex
  Tekijä: Zloza, Andrew, et al.
  Julkaistu: (2013)