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Development of benzo[1,4]oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae

Bacterial biofilms are estimated to be associated with over 65 percent of all nosocomial infections. However, no therapeutics have been approved by the FDA which directly mediate biofilm formation or persistence. Herein we report oxazine 25 as a highly potent inhibitor, disperser and in the presence...

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Detalhes bibliográficos
Publicado no:Chem Commun (Camb)
Main Authors: Warner, Christopher J. A., Cheng, Andrew T., Yildiz, Fitnat H., Linington, Roger G.
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288701/
https://ncbi.nlm.nih.gov/pubmed/25479128
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4cc07003h
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