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Mutational Analysis of the Shigella flexneri O-Antigen Polymerase Wzy: Identification of Wzz-Dependent Wzy Mutants

The O-antigen (Oag) component of lipopolysaccharide (LPS) is a major virulence determinant of Shigella flexneri and is synthesized by the O-antigen polymerase, Wzy(Sf). Oag chain length is regulated by chromosomally encoded Wzz(Sf) and pHS-2 plasmid-encoded Wzz(pHS2). To identify functionally import...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Main Authors: Nath, Pratiti, Tran, Elizabeth Ngoc Hoa, Morona, Renato
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288684/
https://ncbi.nlm.nih.gov/pubmed/25313393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01885-14
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