Zuo Jin Wan reverses P-gp-mediated drug-resistance by inhibiting activation of the PI3K/Akt/NF-κB pathway

BACKGROUND: Zuo-Jin-Wan (ZJW), a traditional Chinese medicine formula, has been identified to be effective against drug resistance in cancer. In the present study, we investigated the effect of ZJW on acquired oxaliplatin-resistant and the PI3K/Akt/NF-κB pathway in vitro. METHODS: We tested the dose...

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Vydáno v:BMC Complement Altern Med
Hlavní autoři: Sui, Hua, Pan, Shu-Fang, Feng, Yu, Jin, Bao-Hui, Liu, Xuan, Zhou, Li-Hong, Hou, Feng-Gang, Wang, Wen-Hai, Fu, Xiao-Ling, Han, Zhi-Fen, Ren, Jian-Lin, Shi, Xiao-Lan, Zhu, Hui-Rong, Li, Qi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288643/
https://ncbi.nlm.nih.gov/pubmed/25085593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6882-14-279
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