Screening ion-channel ligand interactions with passive pumping in a microfluidic bilayer lipid membrane chip

We describe a scalable artificial bilayer lipid membrane platform for rapid electrophysiological screening of ion channels and transporters. A passive pumping method is used to flow microliter volumes of ligand solution across a suspended bilayer within a microfluidic chip. Bilayers are stable at fl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Biomicrofluidics
Main Authors: Saha, Shimul C., Powl, Andrew M., Wallace, B. A., de Planque, Maurits R. R., Morgan, Hywel
Format: Artigo
Jezik:Inglês
Izdano: AIP Publishing LLC 2015
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288537/
https://ncbi.nlm.nih.gov/pubmed/25610515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4905313
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