Combined aliskiren and L-arginine treatment has antihypertensive effects and prevents vascular endothelial dysfunction in a model of renovascular hypertension

Angiotensin II is a key player in the pathogenesis of renovascular hypertension, a condition associated with endothelial dysfunction. We investigated aliskiren (ALSK) and L-arginine treatment both alone and in combination on blood pressure (BP), and vascular reactivity in aortic rings. Hypertension...

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Veröffentlicht in:Braz J Med Biol Res
Hauptverfasser: Santuzzi, C.H., Tiradentes, R.V., Mengal, V., Claudio, E.R.G., Mauad, H., Gouvea, S.A., Abreu, G.R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Associação Brasileira de Divulgação Científica 2014
Schlagworte:
Biomedical Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288495/
https://ncbi.nlm.nih.gov/pubmed/25493385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/1414-431X20144191
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