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Identification of a pKa-regulating motif stabilizing imidazole-modified double-stranded DNA
The predictable 3D structure of double-stranded DNA renders it ideally suited as a template for the bottom-up design of functionalized nucleic acid-based active sites. We here explore the use of a 14mer DNA duplex as a scaffold for the precise and predictable positioning of catalytic functionalities...
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| Publicat a: | Nucleic Acids Res |
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| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288195/ https://ncbi.nlm.nih.gov/pubmed/25520197 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1306 |
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