Site-specific fluorescence dynamics in an RNA ‘thermometer’ reveals the role of ribosome binding in its temperature-sensitive switch function

RNA thermometers control the translation of several heat shock and virulence genes by their temperature-sensitive structural transitions. Changes in the structure and dynamics of MiniROSE RNA, which regulates translation in the temperature range of 20–45°C, were studied by site specifically replacin...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Narayan, Satya, Kombrabail, Mamta H., Das, Sudipta, Singh, Himanshu, Chary, Kandala V. R., Rao, Basuthkar J., Krishnamoorthy, Guruswamy
Format: Artigo
Language:Inglês
Published: Oxford University Press 2015
Subjects:
RNA
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288164/
https://ncbi.nlm.nih.gov/pubmed/25477380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1264
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