CHIP, a carboxy terminus HSP-70 interacting protein, prevents cell death induced by endoplasmic reticulum stress in the central nervous system

Endoplasmic reticulum (ER) stress and protein misfolding are associated with various neurodegenerative diseases. ER stress activates unfolded protein response (UPR), an adaptative response. However, severe ER stress can induce cell death. Here we show that the E3 ubiquitin ligase and co-chaperone Ca...

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Bibliografiska uppgifter
I publikationen:Front Cell Neurosci
Huvudupphovsmän: Cabral Miranda, Felipe, Adão-Novaes, Juliana, Hauswirth, William W., Linden, Rafael, Petrs-Silva, Hilda, Chiarini, Luciana B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2015
Ämnen:
Neuroscience
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4288139/
https://ncbi.nlm.nih.gov/pubmed/25620910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00438
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