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Endocrine Disrupting Chemicals Promote the Growth of Ovarian Cancer Cells via the ER-CXCL12-CXCR4 Signaling Axis
The majority of ovarian cancers over-express the estrogen receptor (ERα) and grow in response to estrogens. We previously demonstrated that ER induction of the chemokine CXCL12 (stromal cell-derived facor-1) is required for estradiol (E2)-stimulated proliferation of human ovarian carcinoma cells. In...
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| Veröffentlicht in: | Mol Carcinog |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4287997/ https://ncbi.nlm.nih.gov/pubmed/22549810 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.21913 |
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