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Application of a reliable and rapid polymerase chain reaction based method in the diagnosis of myotonic dystrophy type 1 (DM1) in India()

DM1 is caused by CTG repeat expansion in the 3′-UTR of the DMPK gene. DM1 patients have expansions of greater than 50 repeats and up to many thousands. The intention of the present study is the establishment of reliable and rapid polymerase chain reaction methodology in early screening of DM1 patien...

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發表在:Meta Gene
Main Authors: Kumar, Ashok, Agarwal, Sarita, Phadke, Shubha R., Pradhan, Sunil
格式: Artigo
語言:Inglês
出版: Elsevier 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4287798/
https://ncbi.nlm.nih.gov/pubmed/25606394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mgene.2013.12.001
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